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High-throughput chemical screening identifies compounds that inhibit different stages of the Phytophthora agathidicida and Phytophthora cinnamomi life cycles

July 2017

Publication: High-throughput chemical screening identifies compounds that inhibit different stages of the Phytophthora agathidicida and Phytophthora cinnamomi life cycles
Author(s): Lawrence, S.A., Armstrong, C.B., Patrick, W.M. and Gerth, M.L.

Here, we have screened over 100 compounds for their anti-oomycete activity, as a potential first step toward identifying new control strategies. Our screening identified eight compounds that showed activity against both Phytophthora species. These included five antibiotics, two copper compounds and a quaternary ammonium cation. These compounds were tested for their inhibitory action against three stages of the Phytophthora life cycle: mycelial growth, zoospore germination, and zoospore motility.

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